The American Heritage® Dictionary of the English Language, 4th Edition
n. A chronic disease of adults marked by enlargement of the bones of the extremities, face, and jaw that is caused by overactivity of the pituitary gland.
n. A chronic disease marked by enlargement of the bones of the extremities, face, and jaw that is caused by over-activity of the pituitary gland.
the GNU version of the Collaborative International Dictionary of English
n. Chronic enlargement of the extremities and face.
The Century Dictionary and Cyclopedia
n. A disease characterized by hypertrophy of the bones and soft tissues of the face and extremities.
WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
n. enlargement of bones of hands and feet and face; often accompanied by headache and muscle pain and emotional disturbances; caused by overproduction of growth hormone by the anterior pituitary gland (due to a tumor)
Word Usage
"It is possible that in acromegaly, in some stages of the disease there may be a hypophyseal diabetes and at others a metahypophyseal diabetes."