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botulin

/ˈbɒtjʊlɪn/ (UK); /ˈbɑːtʃəlɪn/ (US) noun · British & US
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What does botulin mean?

Botulin is an extremely powerful neurotoxin generated by the anaerobic bacterium Clostridium botulinum, the organism responsible for botulism, a rare but life-threatening form of food poisoning. The toxin works by preventing the release of acetylcholine at nerve endings, producing progressive muscle paralysis that can prove fatal if it reaches the muscles controlling breathing. Because it acts with such extraordinary potency, even trace contamination of improperly canned or preserved foods is dangerous, making botulin a central concern of food-safety regulation. Paradoxically, the same paralytic action has been harnessed for therapeutic benefit: purified botulin type A, marketed under names such as Botox, is injected in minuscule doses to relax overactive muscles, treating conditions like blepharospasm and chronic migraine as well as smoothing facial wrinkles. The word derives from the Latin botulus, meaning sausage, a reminder that early outbreaks were linked to tainted sausages.

noun

A potent neurotoxin produced by the bacterium Clostridium botulinum, which causes botulism poisoning by blocking nerve impulses; in purified, minute doses it is used medicinally (as Botox) to treat muscle spasms and reduce wrinkles.

Senses
  1. The neurotoxin produced by Clostridium botulinum that blocks acetylcholine release at neuromuscular junctions, causing paralysis.
  2. Any of the serologically distinct types (A–G) of this toxin.
Example

"The outbreak was traced to home-canned beans contaminated with botulin."

More examples

"Laboratory tests confirmed the presence of botulin in the suspect jar of preserved fish."

"Purified botulin type A is injected in tiny doses to relieve chronic muscle spasm."

Plural botulins

Rarely used; reserved mainly for referring collectively to the different serological types of the toxin rather than multiple quantities.

Example

"Seven antigenically distinct botulins are recognized, labelled A through G."

Did you know?

One of the deadliest natural poisons known — a few nanograms can be lethal — is also injected into millions of foreheads every year in the pursuit of smooth skin.

Reviewed by Deb Chak, Editor. AI-assisted content curated by RJS Tech Solutions LLP.

Etymology of botulin

Botulin derives from the Latin botulus, meaning 'sausage', combined with the protein suffix '-in'. The name reflects the word's late nineteenth-century origins, when researchers investigating fatal cases of sausage poisoning identified the bacterial toxin responsible. The same root gives us botulism, coined around the same period for the disease itself, and survives today in the scientific name of the culprit bacterium, Clostridium botulinum.

Related word forms

How botulin is actually used

Botulin is a technical term used chiefly in medicine, microbiology, and food safety contexts; it functions as an uncountable noun in general use, though the plural 'botulins' appears when referring to its different serological types. In cosmetic and popular usage, the trade name Botox is far more common than the generic term.

Easily confused with botulin

botulism

Botulism is the illness caused by eating or exposure to botulin, which is the toxin itself.

What's another word for botulin?

Words and phrases paired with botulin

botulin toxintype A botulinbotulin antitoxin

Rhymes with botulin