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glycosylated

/ˌɡlaɪkoʊˈsɪleɪtɪd/ adjective · British & US
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What does glycosylated mean?

Glycosylated refers to a type of post-translational modification where a carbohydrate molecule is attached to a protein or lipid molecule. This process, known as glycosylation, is crucial for various cellular functions, including cell signaling, protein stability, and immune response. Glycosylated proteins and lipids are found in cell membranes, where they play a vital role in cell-to-cell communication and recognition. The attachment of carbohydrate molecules to proteins and lipids can affect their function, localization, and stability. Glycosylation is a complex process that involves the coordinated action of multiple enzymes and is essential for maintaining cellular homeostasis. In addition, glycosylated molecules have been implicated in various diseases, including cancer, diabetes, and neurodegenerative disorders. Understanding the mechanisms of glycosylation and its role in cellular processes is essential for developing new therapeutic strategies.

adjective

Having a carbohydrate (sugar) molecule attached to a protein or lipid molecule.

Senses
  1. 1. Having a carbohydrate molecule attached to a protein or lipid molecule.
  2. 2. Modified by the attachment of a carbohydrate molecule.
Example

"The glycosylated proteins in the cell membrane play a crucial role in cell signaling."

More examples

"The glycosylated proteins in the cell membrane play a crucial role in cell signaling."

"The glycosylation of proteins is essential for their proper folding and function."

Reviewed by Deb Chak, Editor. AI-assisted content curated by RJS Tech Solutions LLP.

Etymology of glycosylated

The term 'glycosylated' is derived from the Greek words 'glykos' (sweet) and 'sylē' (molecule). The process of glycosylation was first described in the 1960s, and since then, it has been extensively studied in various fields, including biochemistry, cell biology, and medicine.

Usage notes

Glycosylated is a formal term used in scientific and medical contexts. It is often used to describe the modification of proteins and lipids in cell membranes. In informal contexts, the term 'glycosidated' may be used interchangeably with 'glycosylated'.

Synonyms for glycosylated

Rhymes with glycosylated