What does leukotriene mean?
Leukotriene refers to a type of eicosanoid, a group of signaling molecules that play a crucial role in the inflammatory response. These molecules are derived from arachidonic acid or other polyunsaturated fatty acids and are involved in the pathophysiology of several diseases, including asthma, allergies, and arthritis. Leukotrienes act as inflammatory mediators, promoting inflammation and constriction of airways. The study of leukotrienes has led to a better understanding of the inflammatory response and the development of new treatments for related diseases. Leukotriene modifiers, for example, are used to treat asthma and other respiratory conditions.
nounA type of eicosanoid, a group of signaling molecules made by the enzymatic or non-enzymatic oxidation of arachidonic acid or other polyunsaturated fatty acids.
- A type of eicosanoid involved in inflammation
- A molecule involved in the pathophysiology of certain diseases
"Leukotrienes play a significant role in the inflammatory response and are involved in the pathophysiology of several diseases, including asthma."
"The discovery of leukotrienes has led to a better understanding of the inflammatory response."
"Leukotriene modifiers are used as a treatment for asthma."
countable, used to refer to multiple types or instances of leukotrienes
"The researchers studied the effects of different leukotrienes on airway constriction."
Reviewed by Deb Chak, Editor. AI-assisted content curated by RJS Tech Solutions LLP.
Etymology of leukotriene
The term 'leukotriene' was coined from the Greek words 'leukos,' meaning white, and 'triene,' referring to the three conjugated double bonds in the molecule. Leukotrienes were first discovered in the 1970s as a type of slow-reacting substance (SRS) involved in anaphylaxis. The name reflects the chemical structure of these molecules.
Usage notes
Formal or technical contexts, often used in biology, medicine, or chemistry.