What does oncogene mean?
An oncogene is a gene that has the potential to cause cancer. It is often found in tumor cells and typically results from a mutation in a normal gene. Oncogenes play a crucial role in cancer development and progression, and understanding their function is essential for developing effective treatments. The study of oncogenes has led to significant advances in cancer research and has improved our understanding of the genetic mechanisms underlying this disease. Oncogenes can be activated by various genetic alterations, including mutations, chromosomal translocations, and gene amplification. The identification of oncogenes has also led to the development of targeted therapies, which have shown promise in treating certain types of cancer.
nounA gene that has the potential to cause cancer, often found in tumor cells and typically resulting from a mutation in a normal gene.
- A gene with the potential to cause cancer
- A gene found in tumor cells
"The scientists discovered that the virus had inserted an oncogene into the host cell's DNA, leading to uncontrolled cell growth."
"The researchers studied the role of oncogenes in cancer development."
"The presence of an oncogene in a tumor cell can lead to aggressive cancer growth."
Used as a countable noun, often in scientific and medical contexts.
"The study identified several oncogenes that were associated with aggressive cancer growth."
Reviewed by Deb Chak, Editor. AI-assisted content curated by RJS Tech Solutions LLP.
Etymology of oncogene
The term 'oncogene' was first coined in the 1970s, derived from the Greek words 'onkos,' meaning 'mass' or 'tumor,' and 'gene,' meaning 'origin' or 'producer.' The concept of oncogenes emerged from research on retroviruses, which were found to carry genes that could transform normal cells into cancer cells. The study of oncogenes has since become a major area of research in cancer genetics.
How oncogene is actually used
Typically used in scientific and medical contexts, often in discussions about cancer research and genetics.