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statin

/ˈstætɪn/ noun · British & US
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What does statin mean?

A statin is a type of medication used to lower cholesterol levels and reduce the risk of cardiovascular disease. Statins work by inhibiting the enzyme HMG-CoA reductase, which plays a central role in cholesterol production in the liver. They are commonly prescribed to individuals with high cholesterol or those at risk of heart disease. Statins are often used in conjunction with lifestyle changes, such as diet and exercise, to manage cholesterol levels and reduce cardiovascular risk. The use of statins has been shown to be effective in reducing the risk of heart attacks, strokes, and other cardiovascular events. Overall, statins are a widely used and effective treatment for high cholesterol and cardiovascular disease.

noun

A statin is a type of lipid-lowering medication that inhibits the enzyme HMG-CoA reductase, which plays a central role in cholesterol production in the liver. Statins are commonly used to treat high cholesterol and reduce the risk of cardiovascular disease.

Senses
  1. A type of lipid-lowering medication.
  2. A class of drugs used to treat hypercholesterolemia.
Example

"The doctor prescribed a statin to help lower my cholesterol levels."

More examples

"The patient was prescribed a statin to manage their high cholesterol."

"Statins are commonly used in conjunction with lifestyle changes to reduce cardiovascular risk."

Plural statins

The plural form 'statins' is used when referring to multiple types of statin medications or when discussing the class of drugs as a whole.

Example

"The patient was taking a combination of statins to manage their cholesterol levels."

Reviewed by Deb Chak, Editor. AI-assisted content curated by RJS Tech Solutions LLP.

Etymology of statin

The term 'statin' was coined in 1988, derived from the word 'mevastatin', which was the first compound in this class to be discovered. The name is a portmanteau of 'mevalonate' and 'statin', reflecting the drug's mechanism of action as an inhibitor of HMG-CoA reductase.

Usage notes

Statins are typically used in formal medical contexts, and are often referred to by their generic or brand names (e.g. atorvastatin, simvastatin).

Synonyms for statin

Rhymes with statin