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vancomycin

/ˌvæŋkəˈmaɪsɪn/ noun · British & US
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What does vancomycin mean?

Vancomycin is a glycopeptide antibiotic whose importance lies in its activity against many Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and certain enterococci. Clinicians use intravenous vancomycin for serious infections such as bacteremia, pneumonia, and bone or joint infection, while oral vancomycin is used to treat Clostridioides difficile infection in the bowel. The route matters because oral vancomycin is poorly absorbed from the gastrointestinal tract and therefore does not provide dependable treatment for bloodstream or other systemic infections. Vancomycin can cause kidney impairment, infusion-related reactions, and some forms of antibiotic-associated diarrhea. Its name reflects its reputation for “vanquishing” susceptible bacteria. The drug remains a vital clinical tool, although bacterial resistance and its potential toxicity make careful prescribing essential.

noun

A glycopeptide antibiotic used to treat serious infections caused by susceptible Gram-positive bacteria. Oral vancomycin is used for intestinal infections such as Clostridioides difficile infection, while intravenous vancomycin is used for systemic infections including MRSA bacteremia.

Senses
  1. An antibiotic medicine used to treat certain infections caused by Gram-positive bacteria, including susceptible Staphylococcus aureus, enterococci, and Clostridioides difficile.
Example

"Because the patient's MRSA bloodstream infection had not responded to other antibiotics, the medical team began intravenous vancomycin."

More examples

"The patient with MRSA bacteremia began receiving intravenous vancomycin after blood cultures identified the organism."

"Oral vancomycin was prescribed for the patient's C. difficile infection because the drug acts within the intestine and is poorly absorbed systemically."

Plural vancomycins

The plural is grammatically possible but uncommon; in clinical writing, the noun is normally used in the singular or as a mass noun.

Example

"The study compared two vancomycins produced by different manufacturers."

Did you know?

The name says it all: vancomycin was coined from “vanquish,” honoring its power against susceptible Gram-positive invaders.

Reviewed by Deb Chak, Editor. AI-assisted content curated by RJS Tech Solutions LLP.

Etymology of vancomycin

Vancomycin is a mid-20th-century coined name formed from vanquish and the antibiotic-forming suffix -mycin. The latter reflects Greek mykēs, meaning “fungus” or “mushroom,” a root also represented in the names of several antibiotics. Vanquish came through Old French from Latin vincere, meaning “to conquer,” so the compound name evokes the drug's ability to conquer susceptible infections.

How vancomycin is actually used

This is a specialized pharmacological term used primarily in clinical, scientific, and pharmaceutical contexts. The route of administration is significant: oral vancomycin treats intestinal infection, whereas intravenous vancomycin is used for infections elsewhere in the body.

Words and phrases paired with vancomycin

vancomycin therapyvancomycin treatmentintravenous vancomycinvancomycin-resistant Enterococcus