n. The impairment of the normal capacity of the nervous system for bringing into action one or more active organs, muscular or glandular, or for receiving impressions along one or more sensory paths.n. Figuratively, loss of energy; loss of the power of performing regular functions; the state of being crippled, as in an emergency, or helpless amid any circumstances.n. Paralysis due to an encephalic lesion.n. Muscular pseudohypertrophy.